ClawBio

Automate cell segmentation in fluorescence microscopy images with precision and reproducibility.

Query the ClinPGx API for pharmacogenomic gene-drug data and clinical annotations.

Perform federated variant lookups across multiple genomic databases.

Evidence-based target validation scoring for drug discovery with transparent decision-making.

Create new ClawBio skills using a structured template with validation.

Execute read-only SQL queries against BigQuery public datasets with local result capture and cost safeguards.

Perform bioinformatics analysis on genetic data using ClawBio.

Compute HEIM diversity and equity metrics from genomic data with visualizations and reports.

Search scientific papers and retrieve structured experimental data with 25+ fields per result.

Aggregate public target-level evidence across omics and translational sources for efficient research triage.

Visualize and report bulk RNA-seq and scRNA differential expression results with ease.

Local scVI/scANVI-based single-cell latent embedding and batch-aware integration.

Identify medications from photos and receive personalized dosage guidance based on genotype.

Generate personalized nutrition reports from genetic data for actionable dietary guidance.

Discover and execute 8,000+ bioinformatics tools from Galaxy using natural language queries.

Calculate polygenic risk scores from DTC genetic data using the PGS Catalog.

Local Scanpy pipeline for single-cell RNA-seq analysis, including QC, clustering, and marker discovery.

ClawBio is the first bioinformatics-native AI agent skill library, designed for reproducible and privacy-focused analysis.

Export bioinformatics analyses as reproducible bundles with Conda, Singularity, and Nextflow.

Search and synthesize biomedical literature from PubMed and bioRxiv into structured reports.

Annotate VCF files with ClinVar, gnomAD, and Ensembl VEP to generate detailed variant reports.

Generate offspring genomes through meiotic recombination and mutation analysis.

Automate HLA allele typing from WGS/WES VCF data with structured reporting.

Extract numerical data from scientific figures using advanced image processing techniques.

Detect Neanderthal and Denisovan introgression segments in modern human genomes.

Quickly list all available ClawBio bioinformatics skills with their current status and capabilities.

Meta-agent for bioinformatics that routes requests to specialized sub-skills.

Import DRAGEN-exported Illumina result bundles into ClawBio for local tertiary analysis.

Transform SOUL.md character profiles into synthetic diploid genomes with ease.

Retrieve and manage scientific protocols from protocols.io via a REST API.

Statistical fine-mapping of GWAS loci to identify causal variants and credible sets.

Predict protein structures using Boltz-2 with YAML inputs and generate detailed reports.

Bundled synthetic 20-variant VCF used for demo mode

Semantic search tool for UK Biobank's extensive data fields and publications.

Generate a unified personal genomic profile report from PatientProfile JSON.

Generate personalized pharmacogenomic reports from DTC genetic data in seconds.

Compute epigenetic age from DNA methylation arrays using standardized PyAging clocks.

Streamline Bioconductor package discovery and workflow recommendations for bioinformatics tasks.

Analyze semantic similarity in disease research literature using PubMedBERT embeddings.

Perform two-sample Mendelian Randomisation using GWAS summary statistics for causal inference.

Comprehensive shotgun metagenomics analysis for taxonomy, resistome, and functional pathways.

Perform differential expression analysis on LFQ proteomics data from MaxQuant and DIA-NN outputs.

Interact with Labstep electronic lab notebook data for experiments, protocols, and inventory.

Generates professional clinical PDF reports in Spanish from WES data with interpretation and recommendations.

Generate professional clinical PDF reports from WES data in English.

Score genetic compatibility for male-female pairings in a Genomebook generation.

Aggregate bioinformatics QC reports into a single MultiQC summary.

Automate NGS read QC, alignment, and BAM processing with Seq Wrangler.

Compare your genome to George Church's and estimate ancestry composition using IBS and EM admixture.

Perform ancestry analysis using PCA against the Simons Genome Diversity Project.

Classify germline variants using ACMG/AMP guidelines and generate clinical-grade reports.

Perform differential expression analysis for bulk RNA-seq and pseudo-bulk count matrices.

Quickly generate structured research briefings from PubMed for genes or diseases.

Summarize differential expression results with ranked gene lists and biological themes.

Run a demo of ClawBio skills using built-in sample data.

Find clinical trials for specific genes, variants, or conditions using ClinicalTrials.gov and EUCTR data.