ClawBio

Perform bioinformatics analysis on genetic data using ClawBio.

Annotate VCF files with ClinVar, gnomAD, and Ensembl VEP to generate detailed variant reports.

Automate cell segmentation in fluorescence microscopy images with precision and reproducibility.

Summarize differential expression results with ranked gene lists and biological themes.

Statistical fine-mapping of GWAS loci to identify causal variants and credible sets.

Retrieve and manage scientific protocols from protocols.io via a REST API.

Identify medications from photos and receive personalized dosage guidance based on genotype.

Aggregate bioinformatics QC reports into a single MultiQC summary.

Bundled synthetic 20-variant VCF used for demo mode

Query the ClinPGx API for pharmacogenomic gene-drug data and clinical annotations.

Perform ancestry analysis using PCA against the Simons Genome Diversity Project.

Import DRAGEN-exported Illumina result bundles into ClawBio for local tertiary analysis.

Generate personalized pharmacogenomic reports from DTC genetic data in seconds.

Local Scanpy pipeline for single-cell RNA-seq analysis, including QC, clustering, and marker discovery.

Compare your genome to George Church's and estimate ancestry composition using IBS and EM admixture.

Search scientific papers and retrieve structured experimental data with 25+ fields per result.

Search and synthesize biomedical literature from PubMed and bioRxiv into structured reports.

Comprehensive shotgun metagenomics analysis for taxonomy, resistome, and functional pathways.

Semantic search tool for UK Biobank's extensive data fields and publications.

Local scVI/scANVI-based single-cell latent embedding and batch-aware integration.

ClawBio is the first bioinformatics-native AI agent skill library, designed for reproducible and privacy-focused analysis.

Discover and execute 8,000+ bioinformatics tools from Galaxy using natural language queries.

Execute read-only SQL queries against BigQuery public datasets with local result capture and cost safeguards.

Classify germline variants using ACMG/AMP guidelines and generate clinical-grade reports.

Perform federated variant lookups across multiple genomic databases.

Perform two-sample Mendelian Randomisation using GWAS summary statistics for causal inference.

Generate personalized nutrition reports from genetic data for actionable dietary guidance.

Streamline Bioconductor package discovery and workflow recommendations for bioinformatics tasks.

Extract numerical data from scientific figures using advanced image processing techniques.

Analyze semantic similarity in disease research literature using PubMedBERT embeddings.

Visualize and report bulk RNA-seq and scRNA differential expression results with ease.

Compute epigenetic age from DNA methylation arrays using standardized PyAging clocks.

Generate professional clinical PDF reports from WES data in English.

Transform SOUL.md character profiles into synthetic diploid genomes with ease.

Interact with Labstep electronic lab notebook data for experiments, protocols, and inventory.

Automate HLA allele typing from WGS/WES VCF data with structured reporting.

Aggregate public target-level evidence across omics and translational sources for efficient research triage.

Detect Neanderthal and Denisovan introgression segments in modern human genomes.

Compute HEIM diversity and equity metrics from genomic data with visualizations and reports.

Quickly list all available ClawBio bioinformatics skills with their current status and capabilities.

Find clinical trials for specific genes, variants, or conditions using ClinicalTrials.gov and EUCTR data.

Evidence-based target validation scoring for drug discovery with transparent decision-making.

Automate NGS read QC, alignment, and BAM processing with Seq Wrangler.

Quickly generate structured research briefings from PubMed for genes or diseases.

Generate offspring genomes through meiotic recombination and mutation analysis.

Export bioinformatics analyses as reproducible bundles with Conda, Singularity, and Nextflow.

Perform differential expression analysis on LFQ proteomics data from MaxQuant and DIA-NN outputs.

Score genetic compatibility for male-female pairings in a Genomebook generation.

Generates professional clinical PDF reports in Spanish from WES data with interpretation and recommendations.

Generate a unified personal genomic profile report from PatientProfile JSON.

Create new ClawBio skills using a structured template with validation.

Meta-agent for bioinformatics that routes requests to specialized sub-skills.

Calculate polygenic risk scores from DTC genetic data using the PGS Catalog.

Predict protein structures using Boltz-2 with YAML inputs and generate detailed reports.

Run a demo of ClawBio skills using built-in sample data.

Perform differential expression analysis for bulk RNA-seq and pseudo-bulk count matrices.