ClawBio

Local Scanpy pipeline for single-cell RNA-seq analysis, including QC, clustering, and marker discovery.

Generates professional clinical PDF reports in Spanish from WES data with interpretation and recommendations.

Visualize and report bulk RNA-seq and scRNA differential expression results with ease.

Evidence-based target validation scoring for drug discovery with transparent decision-making.

Generate professional clinical PDF reports from WES data in English.

Find clinical trials for specific genes, variants, or conditions using ClinicalTrials.gov and EUCTR data.

Streamline Bioconductor package discovery and workflow recommendations for bioinformatics tasks.

Retrieve and manage scientific protocols from protocols.io via a REST API.

Perform federated variant lookups across multiple genomic databases.

Meta-agent for bioinformatics that routes requests to specialized sub-skills.

Execute read-only SQL queries against BigQuery public datasets with local result capture and cost safeguards.

Automate cell segmentation in fluorescence microscopy images with precision and reproducibility.

Compute HEIM diversity and equity metrics from genomic data with visualizations and reports.

Quickly list all available ClawBio bioinformatics skills with their current status and capabilities.

ClawBio is the first bioinformatics-native AI agent skill library, designed for reproducible and privacy-focused analysis.

Quickly generate structured research briefings from PubMed for genes or diseases.

Generate offspring genomes through meiotic recombination and mutation analysis.

Query the ClinPGx API for pharmacogenomic gene-drug data and clinical annotations.

Score genetic compatibility for male-female pairings in a Genomebook generation.

Perform differential expression analysis on LFQ proteomics data from MaxQuant and DIA-NN outputs.

Semantic search tool for UK Biobank's extensive data fields and publications.

Analyze semantic similarity in disease research literature using PubMedBERT embeddings.

Annotate VCF files with ClinVar, gnomAD, and Ensembl VEP to generate detailed variant reports.

Compute epigenetic age from DNA methylation arrays using standardized PyAging clocks.

Generate personalized pharmacogenomic reports from DTC genetic data in seconds.

Perform differential expression analysis for bulk RNA-seq and pseudo-bulk count matrices.

Perform two-sample Mendelian Randomisation using GWAS summary statistics for causal inference.

Aggregate bioinformatics QC reports into a single MultiQC summary.

Detect Neanderthal and Denisovan introgression segments in modern human genomes.

Summarize differential expression results with ranked gene lists and biological themes.

Extract numerical data from scientific figures using advanced image processing techniques.

Automate NGS read QC, alignment, and BAM processing with Seq Wrangler.

Identify medications from photos and receive personalized dosage guidance based on genotype.

Run a demo of ClawBio skills using built-in sample data.

Create new ClawBio skills using a structured template with validation.

Perform bioinformatics analysis on genetic data using ClawBio.

Discover and execute 8,000+ bioinformatics tools from Galaxy using natural language queries.

Compare your genome to George Church's and estimate ancestry composition using IBS and EM admixture.

Local scVI/scANVI-based single-cell latent embedding and batch-aware integration.

Predict protein structures using Boltz-2 with YAML inputs and generate detailed reports.

Calculate polygenic risk scores from DTC genetic data using the PGS Catalog.

Generate personalized nutrition reports from genetic data for actionable dietary guidance.

Search and synthesize biomedical literature from PubMed and bioRxiv into structured reports.

Transform SOUL.md character profiles into synthetic diploid genomes with ease.

Search scientific papers and retrieve structured experimental data with 25+ fields per result.

Perform ancestry analysis using PCA against the Simons Genome Diversity Project.

Statistical fine-mapping of GWAS loci to identify causal variants and credible sets.

Generate a unified personal genomic profile report from PatientProfile JSON.

Bundled synthetic 20-variant VCF used for demo mode

Classify germline variants using ACMG/AMP guidelines and generate clinical-grade reports.

Comprehensive shotgun metagenomics analysis for taxonomy, resistome, and functional pathways.

Aggregate public target-level evidence across omics and translational sources for efficient research triage.

Export bioinformatics analyses as reproducible bundles with Conda, Singularity, and Nextflow.

Automate HLA allele typing from WGS/WES VCF data with structured reporting.

Interact with Labstep electronic lab notebook data for experiments, protocols, and inventory.

Import DRAGEN-exported Illumina result bundles into ClawBio for local tertiary analysis.