ClawBio

Evidence-based target validation scoring for drug discovery with transparent decision-making.

Perform bioinformatics analysis on genetic data using ClawBio.

Extract numerical data from scientific figures using advanced image processing techniques.

Create new ClawBio skills using a structured template with validation.

Summarize differential expression results with ranked gene lists and biological themes.

Compute epigenetic age from DNA methylation arrays using standardized PyAging clocks.

Annotate VCF files with ClinVar, gnomAD, and Ensembl VEP to generate detailed variant reports.

Aggregate bioinformatics QC reports into a single MultiQC summary.

Calculate polygenic risk scores from DTC genetic data using the PGS Catalog.

Predict protein structures using Boltz-2 with YAML inputs and generate detailed reports.

Score genetic compatibility for male-female pairings in a Genomebook generation.

Generate offspring genomes through meiotic recombination and mutation analysis.

Perform differential expression analysis for bulk RNA-seq and pseudo-bulk count matrices.

Automate cell segmentation in fluorescence microscopy images with precision and reproducibility.

Interact with Labstep electronic lab notebook data for experiments, protocols, and inventory.

Generate personalized nutrition reports from genetic data for actionable dietary guidance.

Statistical fine-mapping of GWAS loci to identify causal variants and credible sets.

Transform SOUL.md character profiles into synthetic diploid genomes with ease.

Automate NGS read QC, alignment, and BAM processing with Seq Wrangler.

Generate professional clinical PDF reports from WES data in English.

Streamline Bioconductor package discovery and workflow recommendations for bioinformatics tasks.

Execute read-only SQL queries against BigQuery public datasets with local result capture and cost safeguards.

Perform ancestry analysis using PCA against the Simons Genome Diversity Project.

Quickly list all available ClawBio bioinformatics skills with their current status and capabilities.

Visualize and report bulk RNA-seq and scRNA differential expression results with ease.

Local Scanpy pipeline for single-cell RNA-seq analysis, including QC, clustering, and marker discovery.

Detect Neanderthal and Denisovan introgression segments in modern human genomes.

Import DRAGEN-exported Illumina result bundles into ClawBio for local tertiary analysis.

Generate a unified personal genomic profile report from PatientProfile JSON.

Find clinical trials for specific genes, variants, or conditions using ClinicalTrials.gov and EUCTR data.

Perform two-sample Mendelian Randomisation using GWAS summary statistics for causal inference.

Automate HLA allele typing from WGS/WES VCF data with structured reporting.

Compare your genome to George Church's and estimate ancestry composition using IBS and EM admixture.

Compute HEIM diversity and equity metrics from genomic data with visualizations and reports.

Run a demo of ClawBio skills using built-in sample data.

ClawBio is the first bioinformatics-native AI agent skill library, designed for reproducible and privacy-focused analysis.

Aggregate public target-level evidence across omics and translational sources for efficient research triage.

Generates professional clinical PDF reports in Spanish from WES data with interpretation and recommendations.

Identify medications from photos and receive personalized dosage guidance based on genotype.

Search scientific papers and retrieve structured experimental data with 25+ fields per result.

Quickly generate structured research briefings from PubMed for genes or diseases.

Generate personalized pharmacogenomic reports from DTC genetic data in seconds.

Query the ClinPGx API for pharmacogenomic gene-drug data and clinical annotations.

Bundled synthetic 20-variant VCF used for demo mode

Discover and execute 8,000+ bioinformatics tools from Galaxy using natural language queries.

Classify germline variants using ACMG/AMP guidelines and generate clinical-grade reports.

Perform differential expression analysis on LFQ proteomics data from MaxQuant and DIA-NN outputs.

Analyze semantic similarity in disease research literature using PubMedBERT embeddings.

Comprehensive shotgun metagenomics analysis for taxonomy, resistome, and functional pathways.

Export bioinformatics analyses as reproducible bundles with Conda, Singularity, and Nextflow.

Search and synthesize biomedical literature from PubMed and bioRxiv into structured reports.

Meta-agent for bioinformatics that routes requests to specialized sub-skills.

Local scVI/scANVI-based single-cell latent embedding and batch-aware integration.

Semantic search tool for UK Biobank's extensive data fields and publications.

Retrieve and manage scientific protocols from protocols.io via a REST API.

Perform federated variant lookups across multiple genomic databases.